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| SCIENCES DE LA SANTE [ S.S. ] |
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Revue du COSA-CMF |
| Auteurs de l'article |
| NKOLO TFD, EDOUMA BJG, M’FA SK, N’DJEUDJUI C, TAMOH FS, BENGONDO MC |
| Mots Clés |
| suppurative, cervicofacial cellulitis, odontogenic infection, meta-analysis, africa. |
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Num ISSN : 1817-552x [ Trimestriel ] |
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Parution N° 3 du 16-10-2025 |
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Volume : 32 de l'année 2025 |
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SUPPURATIVE ODONTOGENIC CERVICOFACIAL CELLULITIS: AN AFRICAN META-ANALYSIS pp. 17-24. |
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| Introduction: severe odontogenic cervicofacial cellulitis (SOCFC) represents a potentially fatal urgent medical-surgical condition, particularly prevalent in Africa. This meta-analysis aimed to synthesize the available epidemiological, diagnostic, and therapeutic data regarding the management of SOCFC in the African context.
Materials and methods: a comprehensive systematic search was conducted in several major electronic databases, including PubMed, EMBASE, African Journals Online, and Google Scholar, to identify all relevant studies published between January 2000 and December
2024 specifically focusing on frequent surgical complications in odontostomatology in Africa (SOCFC). Data extracted from each study were rigorously collected and organized according to a predefined standardized protocol, ensuring the uniformity and quality of the information analyzed. Statistical analysis of the extracted data was then performed using the specialized software RevMan 5.4 (Review Manager, Version 5.4, The Cochrane Collaboration, 2020), allowing for the synthesis and critical evaluation of the results.
Results: twenty-three studies totaling 1,874 patients were included. The mean age of the patients was 32.7 ± 14.3 years, with a male predominance (62.3%). The prevalence of SOCFC varied from 8.2 to 54.7% of maxillofacial emergencies depending on the region. The mean duration of symptoms was 7.3 days (± 4.6). The main causative dental conditions were mandibular molar involvement (73.8%). Diffuse cellulitis (41.2%) and Ludwig’s angina (22.7%) were the predominant clinical forms. Broad-spectrum empirical antibiotic therapy combined with surgical drainage constituted the standard therapeutic protocol (92.1% of cases). The overall mortality rate was 7.8%, mainly related to mediastinitis (OR=4.72; 95%CI: 2.86-7.81).
Conclusion: this meta-analysis highlights the severity of SOCFC in the African context, characterized by late consultations, severe complications, and significant mortality. Preventive strategies, professional training, and the standardization of therapeutic protocols are necessary to improve the management of this pathology
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